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An acceptable time interval adhering to dosing of LEVITRA for your safe administration of nitrates or nitric oxide donors has not been decided.
The following significant adverse reactions with the usage of LEVITRA (vardenafil) are reviewed in other places within the labeling:
Vardenafil belongs to some classification of medicines generally known as phosphodiesterase 5 (PDE5) inhibitors. These medicines work by blocking the breakdown of the By natural means transpiring material in your body often called cyclic guanosine monophosphate (cGMP).
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It is actually not possible to ascertain whether these situations are linked directly to the usage of PDE5 inhibitors or to other factors [see ADVERSE REACTIONS].
There are no info with using LEVITRA in pregnant Girls to inform any drug-involved risks. In animal copy studies done in Expecting rats and rabbits, no adverse developmental outcomes had been observed with oral administration of vardenafil for the duration of organogenesis at exposures for unbound vardenafil and its main metabolite at roughly a hundred and 29 periods, respectively, the utmost encouraged human dose (MRHD) of 20 mg according to AUC(see Facts).
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